Advanced, Personalised, Multi-Scale Computer

Models Preventing Osteoarthritis


Through OActive project a multi-scale holistic analysis will be adopted, where patient specific information from various levels, including mole

culare (e.g. biochemical/inflammatory biomarkers), cell, tissue and whole body, will be integrated and combined with information from other sources such as, environmental, behavioural and social risk factors to generate robust predictors for new personalised interventions for delaying onset and/or slowing down progression of Osteoarthritis (OA).

Schermata 2018 09 20 alle 18.19.14

OActive targets patient-specific OA prediction and 


interventions by using a combination of mechanical computation models, simuations and big data analytics. Augmentet Reality (AR) empowered interventions will be developed in a personalised framework allowing patients to experience the treatment as more enjoyable, resulting in greater motivation, engagement, and training adherence.





Schermata 2018 09 20 alle 18.20.11